• Geng A+, Wu T+, Cai C+, Song W, Wang J, Yu QC*, Zeng YA*. A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling. Elife. 2020 Aug 4;9:e56434. doi: 10.7554/eLife.56434.

  • Wang D, Wang J, Bai L, Pan H, Feng H, Clevers H, Zeng YA*. Long-term expansion of pancreatic islet organoids from resident Procr+ progenitors. Cell. 2020. Mar 19; 180, 1-14. (2020)
    Commentary: Misra PS and Nostro MC. Islet-Resident Endocrine Progenitors: A New Hope for Beta Cell PROCReation? Cell Stem Cell. 2020 Apr 2;26(4):471-473. doi: 10.1016/j.stem.2020.03.008.

  • Wang J, Wang D, Chu K, Li W*, Zeng YA*. Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium. Nat Commun. Oct 31;10(1):4966 (2019)

  • Cai C, Geng A, Wang M, Yang L, Yu QC*, Zeng YA*. Amphiregulin mediates the hormonal regulation on Rspondin-1 expression in the mammary gland. Dev Biol. 2019 Oct 11. pii: S0012-1606(19)30232-5. (2019)

  • Wang D, Hu X, Liu C, Jia Y, Bai Y, Cai C, Wang J, Bai L, Yang R, Lin C, Liu YR, Li S, Qiao F, Yao L, Chen L, Ge G, Jiang H, Li D, Li L, Chen J, Shao ZM*, Zeng YA*. Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers. Cell Res. Oct;29(10):832-845. (2019)
  • Commentary: NY Fu, JE Visvader*. Halting triple negative breast cancer by targeting PROCR. Cell Res. Nov;29(11):875-876. doi: 10.1038/s41422-019-0245-5. (2019)

  • He L, Yuan L, Sun Y, Wang P, Zhang H, Feng X, Wang Z, Zhang W, Yang C, Zeng YA, Zhao Y, Chen C, Zhang L*. Glucocorticoid Receptor Signaling Activates TEAD4 to Promote Breast Cancer Progression. Cancer Res. Sep 1;79(17):4399-4411. (2019)

  • Malinverno M, Maderna C, Abu Taha A, Corada M, Orsenigo F, Valentino M, Pisati F, Fusco C, Graziano P, Giannotta M, Yu QC, Zeng YA, Lampugnani MG, Magnusson PU, Dejana E*. Endothelial cell clonal expansion in the development of cerebral cavernous malformations. Nat Commun. Jun 24;10(1):2761. (2019)

  • Liu Q, Liu K, Cui G, Huang X, Yao S, Guo W, Qin Z, Li Y, Yang R, Pu W, Zhang L, He L, Zhao H, Yu W, Tang M, Tian X, Cai D, Nie Y, Hu S, Ren T, Qiao Z, Huang H, Zeng YA, Jing N, Peng G, Ji H, Zhou B*. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet. Feb 18. doi: 10.1038/s41588-019-0346-6. (2019)

  • Song W, Wang R, Jiang W, Yin Q, Peng G, Yang R, Yu QC, Chen J, Li J, Cheung TH, Jing N, Zeng YA*. Hormones induce the formation of luminal-derived basal cells in the mammary gland. Cell Res. Mar;29(3):206-220. (2019)

  • Zhang R, Ma H, Gao Y, Wu Y, Qiao Y, Geng A, Cai C, Han Y, Zeng YA, Liu X, Ge G*. Th-POK regulates mammary gland lactation through mTOR-SREBP pathway. PLoS Genet. Feb 8;14(2):e1007211. doi: 10.1371/journal.pgen.1007211. (2018)

  • Wang D, Liu C, Wang J, Jia Y, Hu X, Jiang H, Shao ZM, Zeng YA*. Protein C receptor stimulates multiple signaling pathways in breast cancer cells. J Biol Chem. Jan 26;293(4):1413-1424. (2018)

  • Liu W, Wu T, Dong X, Zeng YA*. Neuropilin-1 is upregulated by Wnt/β-catenin signaling and is important for mammary stem cells. Sci Rep. Sep 8;7(1):10941. (2017)

  • Yu QC, Song W, Lai D, Zeng YA*. A Novel Mammary Fat Pad Transplantation Technique to Visualize the Vessel Generation of Vascular Endothelial Stem Cells. J Vis Exp. Aug 3;(126). (2017)

  • Yu QC, Verheyen EM, Zeng YA*. Mammary Development and Breast Cancer: A Wnt Perspective. Cancers. Jul 13;8(7). pii: E65. doi: 10.3390/cancers8070065. (2016)

  • Yu QC, Song W, Wang D, Zeng YA*. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Research. Jul 1. doi: 10.1038/cr.2016.85. (2016)
    Commentary: Gur-Cohen S, Lapidot T. Vascular Procr+ stem cells: Finding new branches while looking for the roots. Cell Research Oct;26(10):1071-1072.(2016)

  • Zeng L+, Cai C+, Li S, Yu QC, Wang W, Li Y, Chen J, Zhu X*, Zeng YA*. Essential roles of Cyclin Y-like 1 and Cyclin Y in dividing Wnt-responsive mammary stem/progenitor cells. PLOS Genetics. May 20;12(5):e1006055 (2016)

  • Wang D, Cai C, Dong X, Yu QC, Zhang XO, Yang L, Zeng YA*. “Identification of Multipotent Mammary Stem Cells by Protein C Receptor Expression.” Nature. 2015 Jan 1;517(7532):81-4.

  • Cai C, Yu QC, Jiang W, Liu W, Song W, Yu H, Zhang L, Yang Y, Zeng YA*. “R-spondin1 is a novel hormone mediator for mammary stem cell self-renewal.” Genes Dev. 2014 Sep 26;28: 2205–2218.

  • Harburg G, Compton J, Liu W, Iwai N, Zada S, Marlow R, Strickland P, Zeng YA, Hinck L*. “SLIT/ROBO2 Signaling Promotes Mammary Stem Cell Senescence by Inhibiting Wnt Signaling.” Stem Cell Reports. 2014 Sep 9;3(3):385-93.

  • Jan TA, Chai R, Sayyid ZN, van Amerongen R, Xia A, Wang T, Sinkkonen ST, Zeng YA, Levin JR, Heller S, Nusse R, Cheng AG. “Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells.” Development. 2013 Mar;140(6):1196-206.

  • Zeng YA*. (2011) “Beyond nutrients and bonding: p63-positive progenitors in breast milk.” Cell Cycle. 2011 Feb 15;10(4):579-8.

  • Zeng YA. and Nusse R*. “Wnt proteins serve as self-renewal factors for mammary stem cells and promote their long-term expansion in culture.” Cell Stem Cell. 2010 Jun 4;6(6):568-77

  • Minear S., Leucht P., Jiang J., Liu B., Zeng A., Fuerer C., Nusse R., and Helms J.A. “Wnt proteins promote bone regeneration” Science Translational Medicine. 2010 Apr; 28;2(29):29ra30.

  • Nusse R., Fuerer C., Ching W., Harnish K., Logan C., Zeng A., Ten Berge D., Kalani Y. (2008) “Wnt Signaling and Stem Cell Control.” Cold Spring Harb Symp Quant Biol. 2008;73:59-66

  • Zeng YA., Rahnama M., Wang S., Lee W., Verheyen E.M. “Inhibition of Drosophila Wg signaling involves competition between Mad and Armadillo/beta-catenin for dTcf binding.” PLoS ONE. 2008 Dec; 3(12):e3893

  • Zeng YA., Rahnama M., Wang S., Sosu-Sedzorme W., Verheyen E.M. “Drosophila Nemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulation.” Development. 2007 Jun; 134(11):2061-71.

  • Zeng YA. and Verheyen E.M. “Nemo is an inducible antagonist of Wingless signaling during Drosophila wing development.” Development. 2004 Jun; 131(12):2911-20.